Aortic lesions after Radiofrequency and Cryoballoon Therapy In patients undergoing Catheter ablation of Atrial Fibrillation

Aortic lesions after Radiofrequency and Cryoballoon Therapy In patients undergoing Catheter ablation of Atrial Fibrillation - ARCTIC AF

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00013510

Enrollment

Registered

2017-12-04

Start date

2018-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I48.0

Interventions

Group 1: Patients with paroxysmal atrial fibrillation randomized to the cryo-ablation group receive aortic MRI 24h prior to ablation and cryo-ablation at the following day. The day after the procedur

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Included are all patients (> 18 years) undergoing pulmonary vein isolation using radiofrequency energy or cryo-energy within the planned study period of 12 months and agreeing to participate in the study. It is planned to include 60 ablated patients (1: 1, 30 patients with RF ablation and 30 patients with cryoballoon therapy.

Exclusion criteria

Exclusion criteria: There should be no contraindications for anticoagulation or magnetic resonance imaging.

Design outcomes

Primary

Measure	Time frame
The aim of the study is to optimize the safety of pulmonary venin insolation performed by cryogenic or radiofrequency energy with respect to aortic lesions. The endpoint is the detection of aortic lesions after radiofrequency or cryo ablation. The first aortic MRI is planned on the day before ablation and serves as a baseline, then the procedure itself is performed on the following day. The second MRI is performed on the first postoperative day.	—

Measure

Time frame

The aim of the study is to optimize the safety of pulmonary venin insolation performed by cryogenic or radiofrequency energy with respect to aortic lesions. The endpoint is the detection of aortic lesions after radiofrequency or cryo ablation. The first aortic MRI is planned on the day before ablation and serves as a baseline, then the procedure itself is performed on the following day. The second MRI is performed on the first postoperative day.

—

Secondary

Measure	Time frame
Collection of predictors that favor aortic lesions.	—

Countries

Germany

Contacts

Public ContactBarbara Bellmann

Herzzentrum der Uniklinik Köln

barbara.bellmann@uk-koeln.de0049 221 47832396

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026