Influence of vitamin D administration on the intestinal bacterial composition in CD patients and healthy controls

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00013485

Enrollment

Registered

2017-12-04

Start date

2016-11-15

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's disease K50

Interventions

Group 1: Crohn's disease: The intervention was carried out by means of decristol 20,000 IU, every two days up to a target level between 100 and 150 nmol/l. At higher values, vitamin D substitution was

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Crohn's disease with vitamin D deficiency Healthy controls with vitamin D deficiency

Exclusion criteria

Exclusion criteria: patient does not want to participate in the study

Design outcomes

Primary

Measure	Time frame
The effect of vitamin D substitution on the intestinal bacterial composition in patients and controls with vitamin D deficiency has been studied. The examination was performed before vitamin D substitution (week 0), after week 1, week 2, week 3 and week 4. The stool samples were analyzed via NGS (next generation sequencing).	—

Countries

Germany

Contacts

Public ContactHolger Schäffler

Universitätsklinikum Rostock

holger.schaeffler@med.uni-rostock.de00493814947490

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026