Anxiety disorders: Social Phobia, Generalized anxiety disorder, Panic disorder/ Agoraphobia F40.1 F41.1 F41.0 F40.01
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of an Anxiety disorder (SP, Panic/Agoraphobia, GAD, SCID-I) Anxiety disorder must be primary diagnosis (most severe disorder according to ADIS-IV) Patients with anxiety disorders with comorbid disorders will be included, provided that the anxiety disorder is the primary diagnosis, thus ensuring a clinically representative sample age: 18 to 70 years Informed consent
Exclusion criteria
Exclusion criteria: psychotic disorder prominent risk of self-harm acute substance related disorders personality disorders except for avoidant and dependent personality disorder (SCID-II) Posttraumatic Stress Disorder (PTSD) and/or sexual abuse in childhood organic mental disorder severe medical conditions concurrent psychotherapeutic treatment psychopharmacological treatment (stable medical treatments (e.g. SSRI without dose adaptation are permitted)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Global Impression (CGI-scale) after treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints: Anxiety (Mobility index, MI, Body Sensations Questionnaire, BSQ, Agoraphobic Cognitions Questionnaire, ASQ, Liebowitz Social Anxiety Scale, LSAS, Penn State Worry Questionnaire, PSWQ), depression (PHQ-9), quality of life and social functioning (EQ-5D), distress (global severity index, SCL-90), Emotion regulation skills (SEK-27), resilience (RS-11), Working alliance (WAI-12R). Therapists and patients will be asked for the feasibility and acceptance of the treatment (ZUF-8) Safety: Description of serious adverse events and drop-outs Assessments at baseline, after 8 sessions, after 16 sessions, and after 25 sessions (post-treatment), 3 months after end of treatment. | — |
Countries
Germany
Contacts
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz