Evaluation of novel radiation dose reduction strategies on image quality and diagnostic accuracy of abdominal CT imaging in the settings of acute abdomen

Evaluation of novel radiation dose reduction strategies on image quality and diagnostic accuracy of abdominal CT imaging in the settings of acute abdomen - LDCT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00013366

Enrollment

180

Registered

2019-02-27

Start date

2019-02-27

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient with clinical indication for abdominal computer tomography (with contrast agent)

Interventions

Group 1: 70 kVp + high pitch + reconstruction technique ADMIRE Group 2: Low-Dose CT Abdomen Care kV+ low mAs + reconstruction technique ADMIRE Group 3: Dual-Energy-CT 150/80 + low mAs + reconstruction

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. man and woman 2. clinical indication for abdominal computer tomography (contrast enhanced) 3. laboratory parameters in compliance with internal guidelines (creatinine, GFR) 4. age =18 years, 5. informed consent

Exclusion criteria

Exclusion criteria: 1. persons who are incapable of giving informed consent 2. Pregnant and nursing woman 3. contraindication for iodine-containing contast agents 4. impaired renal function 5. claustrophobic patients

Design outcomes

Primary

Measure	Time frame
Determination of the diagnostic accuracy of 3 independent, different low-dose CT protocols in comparison to the established standard CT protocol as part of a CT examination.	—

Secondary

Measure	Time frame
Radiation dose/ imaging quality of three different low-dose protocols in comparison with the standard CT protocol	—

Countries

Germany

Contacts

Public ContactAhmed Othman

Uniklinikum Tübingen, Abteilung f. Diagnostische und Interventionelle Radiologie

ahmed.othman@med.uni-tuebingen.de07071 29-68624

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026