Clinical relevance of bacteraemia with vancomycin-resistant enterococcus vs. vancomycin-sensible enterococcus in patients after orthotopic liver transplantation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00013285

Enrollment

200

Registered

2018-03-13

Start date

2017-10-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthotopic liver transplantation, Bacteremia, vancomycin resistant enterococcus, vancomycin sensible enterococcus, multidrug resistant pathoge, enterococcus spp, Mortalität

Interventions

Group 1: Retrospective, monocentric cohort study. Inclusion criteria: Age > 18 years, orthotopic liver Transplantation and VSE-BSI between 01/01/2007 and 12/31/2016. Follow-up for 30 days after onset

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: All patients above the age of 18 who got a orthotopic liver transplantation and suffered from a bloodstream infection with VRE or/and VSE between 01/01/2007 and 12/31/2016.

Exclusion criteria

Exclusion criteria: Age < 18 years and not fullfill inclusion criteria

Design outcomes

Primary

Measure	Time frame
Are patients after OLT (orthotopic liver transplantation) within 30 days after blood stream infection with vancomycin resistant enterococcus at higher risk to die compared to patients with vancomycin sensible enterococcus?	—

Secondary

Measure	Time frame
1. Is the hospital stay of OLT patients after a blood stream infection with vancomycin resistant enterococcus longer then after a blood stream infection with vancomycin sensible enterococcus? 2. Are patients after OLT within 30 days after a bacteremia with vancomycin resistant enteroccous at higher risk of multi organ failure then patients with a bacteremia with vancomycin sensible enterococcus?	—

Countries

Germany

Contacts

Public ContactThorsten Brenner

Klinik für AnästhesiologieUniversitätsklinikum Heidelberg

thorsten.brenner@med.uni-heidelberg.de+49 (0) 6221-56 39418

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 28, 2026