Standardization of new MRI-Methods Investigating Myocardial Anatomy and Function from Images of Different MRI-Providers

Standardization of new MRI-Methods Investigating Myocardial Anatomy and Function from Images of Different MRI-Providers - Traveling Volunteers

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00013253

Enrollment

Registered

2018-01-18

Start date

2017-12-27

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy volunteers

Interventions

Group 1: All 15 volunteers are going to be examined at the German Heart Institute using a 3.0 Tesla MRI scanner of the company Philips. A consistent MRI protocol is used, which takes approx. 40 minute

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age >18 and <66, signed informed consent, existing health insurance, normal 12-channel-ECG, normal blood pressure behavior

Exclusion criteria

Exclusion criteria: Claustrophobia, Pregnancy, Intrauterine device as contraceptive method, Dysrhythmias, Non MRI-suitable implants or foreign bodies, cardiovascular disease, regular MRI-contraindications

Design outcomes

Secondary

Measure	Time frame
Intra-vendor reproducibility of varying cardiac MRI investigation methods and comparison of new developed methods to established cine-SSFP-scans	—

Primary

Measure	Time frame
The primary outcome is to determine the inter-vendor reproducibility of varying cardiac MRI investigation methods, measured at MRI-scanners of the leading vendors (SIEMENS, Philips, GE). The images acquired with the different imaging methods (SENC, T1-Mapping, T2-Mapping, T2*-Mapping and 4D-Flow) are going to be post-processed and quantitative values calculated (e.g. myocardial strain in % from the SENC-images). Using statistical methods to determine comparability and repeatability, the results of the exams are going to be compared with regard to the varying MRI-scanners.	—

Measure

Time frame

The primary outcome is to determine the inter-vendor reproducibility of varying cardiac MRI investigation methods, measured at MRI-scanners of the leading vendors (SIEMENS, Philips, GE). The images acquired with the different imaging methods (SENC, T1-Mapping, T2-Mapping, T2*-Mapping and 4D-Flow) are going to be post-processed and quantitative values calculated (e.g. myocardial strain in % from the SENC-images). Using statistical methods to determine comparability and repeatability, the results of the exams are going to be compared with regard to the varying MRI-scanners.

—

Countries

Germany

Contacts

Public ContactJennifer Erley

Deutsches Herzzentrum Berlin

jennifer.erley@charite.de+4915157487213

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026