Effects of a noisy galvanic vestibular stimulation on the vestibulospinal reflex threshold in patients with bilateral vestibulopathy

Effects of a noisy galvanic vestibular stimulation on the vestibulospinal reflex threshold in patients with bilateral vestibulopathy - BVPGVS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00013242

Enrollment

Registered

2017-10-26

Start date

2017-10-30

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H81.8

Interventions

Group 1: White noise galvanic vestibular stimulation (GVS) at an intensity of 80% of the individual cutaneous threshold for GVS. GVS is applied for the whole duration of the reflex threshold testing (

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Neurological approved bilateral vestibulopathy

Exclusion criteria

Exclusion criteria: Auditory, neurological, cardiovascular or orthopedic diseases

Design outcomes

Primary

Measure	Time frame
Change in the vestibulospinal reflex threshold. The reflex threshold will be determined by a psychometric test procedure. Accordingly, the vestibulospinal reflex responses (trunk movements) to a vestibular stimulus (sinusoidal galvanic vestibular stimulation (1 Hz)) at varying amplitudes (0 to 1.9 mA) will be measured (by means of motion sensors attached to the forehead and chest) and the smallest stimulus amplitude that elicits a reflex response will be psychometrically determined. This amplitude will be defined as the vestibulospinal reflex threshold. The threshold test lasts for ~ 5 minutes.	—

Measure

Time frame

Change in the vestibulospinal reflex threshold. The reflex threshold will be determined by a psychometric test procedure. Accordingly, the vestibulospinal reflex responses (trunk movements) to a vestibular stimulus (sinusoidal galvanic vestibular stimulation (1 Hz)) at varying amplitudes (0 to 1.9 mA) will be measured (by means of motion sensors attached to the forehead and chest) and the smallest stimulus amplitude that elicits a reflex response will be psychometrically determined. This amplitude will be defined as the vestibulospinal reflex threshold. The threshold test lasts for ~ 5 minutes.

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Countries

Germany

Contacts

Public ContactRoman Schniepp

Department of Neurology & German Center for Vertigo and Balance Disorders, Ludwig-Maximilians-University Munich

Roman.Schniepp@med.uni-muenchen.de0049 (0)89 4400 72486

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026