Gene expression in psoriasis - Post-analyses of the PSORITUS study

Gene expression in psoriasis - Post-analyses of the PSORITUS study - Post-analyses of PSORITUS study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00013229

Enrollment

Registered

2017-10-26

Start date

2017-11-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

L40.0

Interventions

Group 1: Psoriasis-Patients without Pruritus: skin biopsy performed once for genetic analysis Group 2: Psoriasis-Patients with pruritus: use of the data (genetic analysis) of the Psoritus study

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with psoriasis vulgaris (L40.0) without pruritus (group 1) and with pruritus (group 2, historical control group from the Psoritus study)

Exclusion criteria

Exclusion criteria: Patients younger than 18 years. Patients who cannot complete the questionnaires due to physical or psychiatric diseases. Patients with reduced consciousness. Patients who don't understand German.

Design outcomes

Primary

Measure	Time frame
The aim of the study is to compare the expression of genes of olfactory receptors and of barrier associated genes within the skin between patients with psoriasis suffering from pruritus and patients with psoriasis, but no pruritus. Data will be collected once by means of a skin biopsy.	—

Countries

Germany

Contacts

Public ContactManuel Pereira

Klinik für Hautkrankheiten und Kompetenzzentrum chronischer Pruritus (KCP), Universitätsklinikum Münster

juckreizambulanz@ukmuenster.de00492518356501

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026