The impact of sleep on the migratory potential of T cells

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00013226

Enrollment

Registered

2017-11-30

Start date

2018-01-16

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Group 1: Subjects spend 24 hours in the sleep lab, where they are allowed to sleep between 23:00 and 7:00 h. Blood samples for measurement of the migration potential of T cells are collected every 4 h

Eligibility

Sex/Gender

All

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Body mass index between 20 - 25 kg/m2, non-smokers

Exclusion criteria

Exclusion criteria: Acute or chronic illness, shift or night work in the last 6 weeks, sleep disorders, smoking, drug intake (except contraceptives)

Design outcomes

Primary

Measure	Time frame
- Measurement of the migratory potential of different T cell subsets - Migration will be measured using a standard, ex vivo migration assay - T cell subsets will be differentiated by flow cytometry - Measurements will take place every 4 hours during the 24-hour experimental sessions	—

Secondary

Measure	Time frame
- Sleep-dependent hormones (cortisol, growth hormone, and prolactin) will be measured using Standard enzyme-linked immunosorbent assays (ELISA).	—

Countries

Germany

Contacts

Public ContactEstefania Martinez Albert

Institute of Medical Psychology and Behavioural Neurobiology

estefania.martinez-albert@uni-tuebingen.de+49 7071 29-88928

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026