DMEK Replacement of Peribulbar Anaesthesia (DROP) Trial: a controlled, observerblinded, non-inferiority trial

DMEK Replacement of Peribulbar Anaesthesia (DROP) Trial: a controlled, observerblinded, non-inferiority trial - DROP (Dmek Replacement Of Peribulbar anaesthesia )

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00013212

Enrollment

Registered

2017-12-18

Start date

2017-10-17

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H18.5

Interventions

Group 1: 30 DMEK (Descemet Membrane Endothelial Keratoplasty) patients in topical anaesthesia (Oxybuprocain 0,4% Drops and Lidocainhydrochlorid-gel 2%) Group 2: 30 DMEK patients in peribulbar anesthe

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients requiring a DMEK surgery who are willing to participate in the study.

Exclusion criteria

Exclusion criteria: - Physical or mental conditions which would impair a regular follow up visit - excessive fear of surgical pain - ocular conditions interfering with the surgery such as aphakia, anterior chamber IOL, defects due to trauma, corneal scars or post pars plana vitrectomy

Design outcomes

Primary

Measure	Time frame
Pain sensation during surgery measured on a visual analogue scale	—

Secondary

Measure	Time frame
Pain sensation during anaesthesia, duration of surgery, intra and post-surgical complications, endothelial density, visual acuity, transplant rejection rate	—

Countries

Germany

Contacts

Public ContactDaniel Pilger

Charité Campus Virchow-Klinikum

daniel.pilger@charite.de030 450 554 202

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026