Salivary cortisol and autonomic nervous system reactivity to relaxation exercises in palliative care

Salivary cortisol and autonomic nervous system reactivity to relaxation exercises in palliative care - PAL-CORT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00013135

Enrollment

Registered

2017-12-04

Start date

2018-02-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

8-982 Palliativmedizinische Komplexbehandlung OPS 8-98e Spezialisierte stationäre palliativmedizinische Komplexbehandlung

Interventions

Group 1: Relaxation exercise: Single mindfulness exercise for 20 minutes via headphones (saliva samples before the intervention (T0), after the intervention (T1), 20 minutes after the intervention (T2

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Capacity to provide consent - Tumor disease - Sufficient understanding of German or English language

Exclusion criteria

Exclusion criteria: - Final stage of the disease - Cognitive, attentional or auditive impairments (ICD: C71, C72, G93.80, H90, H91) - Manifest psychiatric disease (ICD: F00 – F99)

Design outcomes

Primary

Measure	Time frame
Reactivity of salivary cortisol: T0 at the beginning, T1 after 20 minutes, T2 after 40 minutes, T3 after 60 minutes	—

Secondary

Measure	Time frame
- Reactivity of alpha-amylase 8T0 at the beginning, T1 after 20 minutes, T2 after 40 minutes, T3 after 60 minutes) - Changes in heart rate variability (continously from T0 to T3) - Changes in peripheral blood volume (continously from T0 to T3) - Changes in subjective well-being (T0 at the beginning, T1 after 20 minutes, T2 after 40 minutes, T3 after 60 minutes) - Changes in subjective stress (T0 at the beginning, T1 after 20 minutes, T2 after 40 minutes, T3 after 60 minutes)	—

Measure

Time frame

- Reactivity of alpha-amylase 8T0 at the beginning, T1 after 20 minutes, T2 after 40 minutes, T3 after 60 minutes) - Changes in heart rate variability (continously from T0 to T3) - Changes in peripheral blood volume (continously from T0 to T3) - Changes in subjective well-being (T0 at the beginning, T1 after 20 minutes, T2 after 40 minutes, T3 after 60 minutes) - Changes in subjective stress (T0 at the beginning, T1 after 20 minutes, T2 after 40 minutes, T3 after 60 minutes)

—

Countries

Germany

Contacts

Public ContactMarco Warth

Institut für Medizinische Psychologie, Zentrum für Psychosoziale Medizin, UniversitätsKlinikum Heidelberg

marco.warth@med.uni-heidelberg.de06221-568135

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 10, 2026