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Comparison of the influence of olfactory stimulation with vanilla, breast milk or formula odor on the nasogastric tube weaning of preterm and term born infants

Comparison of the influence of olfactory stimulation with vanilla, breast milk or formula odor on the nasogastric tube weaning of preterm and term born infants

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00013093
Enrollment
150
Registered
2017-11-17
Start date
2018-02-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

P07.3 P92

Interventions

Group 1: Vanilla: The examination takes place during the stationary stay of the participants. Due to insufficient oral food intake, the premature infants are fully or partially nourished by nasogastri
3g in 100ml Group 2: Food Odor: Before each feeding, a smell is presented to the participants for approx. 10 seconds by means of cotton padding by absorbing and presenting a small amount of mother's m

Sponsors

Universitätsklinikum Carl Gustav Carus
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: • Premature / newborn:> 27 SSW • Complete nutrition or partial nutrition via nasogatric tube • Stable vital parameters • Consent of parents or legal guardians

Exclusion criteria

Exclusion criteria: • Intensive medical monitoring / treatment • intubation • ventilation • Severe illness (sepsis, NG infection, complex heart defects) • Need of the cotecholamines • Birth <27 SSW

Design outcomes

Primary

MeasureTime frame
primary outcome is the total oral nutrition of infants over a time of minimum 24 hours -> duration of tube feeding

Secondary

MeasureTime frame
secondary we take a look at bodyweight, amount of nutrition by gavage-, bottle- and breastfeeding until the end of hospitalization, percentage of odor presentation

Countries

Germany

Contacts

Public ContactValentin A. Schriever

Uniklinikum Carl Gustav Carus Dresden, Neuropädiatrie

valentin.schriever@uniklinikum-dresden.de0351/458 2230

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026