L29.9
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with chronic pruritus (L29.9), pruritus intensity NRS (0-10) max. past 24h =3
Exclusion criteria
Exclusion criteria: Patients under 18 years of age; -acute exacerbation of dermatosis, cutaneous infections - pregnancy or lactation -anamnestic drug consumption, alcohol dependency, drug abuse Exclusion criteria in patients with additional planned skin biopsy: - Allergy to local anesthetics, -inclination to keloids
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Analysis of the change sensitivity of the LMS from day 1 and day 14, correlation of the LMS with the density of intraepidermal nerve fibers on day 1 and day 14. | — |
Primary
| Measure | Time frame |
|---|---|
| Validation of LMS (Labeled Magnitude Scale) in chronic pruritus via correlation with the already validated pruritus intensity scales (visual analogue scale, numerical rating scale, verbal rating scale), correlation with restriction of the quality of life (measured by ItchyQoL, DLQI, 5PLQ), retest analyzes of LMS on day 1 t=0 and t=30-60min | — |
Countries
Germany
Contacts
Klinik für Hautkrankheiten und Kompetenzzentrum Chronischer Pruritus