Prospective evaluation of disease free survival and Quality of Life following microvascular reconstruction in early oral squamous cell carcinoma

Prospective evaluation of disease free survival and Quality of Life following microvascular reconstruction in early oral squamous cell carcinoma - PROCURE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00013041

Enrollment

Registered

2017-09-19

Start date

2017-11-01

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C06.9

Interventions

Group 1: Surgical therapy following current therapeutical Guidelines (Tumor removal and reconstruction using autologous microvascular transplants). Regular clinical follow up every month and MRI (head

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Squamous cell carcinoma of the oral cavity with T-Stage T1 or T2 and clinically negative neck node Status (cN0) Surgical Treatment via Tumor resection, Neck Dissection and microvacular reconstruction Minimum Age: 18 years

Exclusion criteria

Exclusion criteria: Recurrence of Prior oral squamous cell carinoma Lack of understanding or legal Age for written consent

Design outcomes

Primary

Measure	Time frame
Disease free survival (DFS) for 24 months following Primary therapy evaluated by regular clinical and MRI examinations	—

Secondary

Measure	Time frame
Postoperative Quality of Life (QLQ-C30 and QLQ-H&N35) 3, 6, 12, 18 and 24 months after Primary therapy in comparison to baseline. Tumorrelated cause of death	—

Countries

Germany

Contacts

Public ContactJulius Moratin

Klinik und Poliklinik für Mund-, Kiefer- und GesichtschirurgieKopfklinikUniversitätsklinikum Heidelberg

julius.moratin@med.uni-heidelberg.de06221-56-34444

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026