Relation of structural and material properties of bone between pelvic bone and fracture-relevant sites in patients with severe renal insufficiency - an exploratory study

Relation of structural and material properties of bone between pelvic bone and fracture-relevant sites in patients with severe renal insufficiency - an exploratory study - CKD-BONE

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00013032

Enrollment

Registered

2017-09-22

Start date

2017-09-22

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N18 N25

Interventions

Group 1: Bone samples will be taken from deceased patients who had severe chronic renal insufficiency, and will be investigated by the use of material research methods such as: qBEI or Raman spectrosc

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Adults with severe chronic renal insufficiency (glomerular filtration rate <30 [ml / min / 1.73 m2] with or without dialysis) are included. • Patient with provided informed consent, obtained before his death.

Exclusion criteria

Exclusion criteria: Known genetic-related bone disease in the anamnesis

Design outcomes

Primary

Measure	Time frame
This study should gain new insights into the relation between architecture and material properties of bone at different skeletal sites. As it is not clear whether the parameters measured from the iliac crest allow conclusions to be drawn about fracture-relevant skeletal sites (femoral neck, mid-shaft, head, vertebral body and forearm) in patients with severe renal insufficiency, this relevant question will be addressed.	—

Measure

Time frame

This study should gain new insights into the relation between architecture and material properties of bone at different skeletal sites. As it is not clear whether the parameters measured from the iliac crest allow conclusions to be drawn about fracture-relevant skeletal sites (femoral neck, mid-shaft, head, vertebral body and forearm) in patients with severe renal insufficiency, this relevant question will be addressed.

—

Countries

Austria

Contacts

Public ContactJohannes Werzowa

Ludwig Boltzmann-Institut für Osteologie,1. Medizinische Abteilung Hanusch-Krankenhaus

johannes.werzowa@osteologie.at0043-1-91021-85081

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026