Evaluation of metabolic bone disease and fracture prevalence in patients with Crohn’s disease

Evaluation of metabolic bone disease and fracture prevalence in patients with Crohn’s disease - CROHN-BONE

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00013028

Enrollment

218

Registered

2017-09-14

Start date

2017-09-14

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K50.9 M82

Interventions

Group 1: Patients with Crohn's disease: Bone density is measured by means of DXA and by means of questionnaires (age, weight, etc.). Clinical activity index in Crohn's disease (CDAI), lab parameters (

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with Crohn´s disease at least 18 years old Control subjects will be recruited from a preventive medical examination program.

Exclusion criteria

Exclusion criteria: • Critically or terminally ill patients. • Unable to comply with study protocol. • Pregnancy (positive urine pregnancy test)

Design outcomes

Primary

Measure	Time frame
Bone Mineral Density by DXA (only in patients with Crohn's disease)	—

Secondary

Measure	Time frame
Questionnaires (Age, weight, height,CD diagnosis date and history, Gender, Current and preceding medications, Comorbidities, Fracture history in 1st degree relatives, Smoking and Alcohol status, Number of flare-ups requiring a visit to the physician and/or corticosteroid use during the preceding year, Lifestyle factors including, history of fractures, BMI, and dietary factors, OSTEO-CHECK and IBDQ-D questionnaire), CDAI (Crohn's Disease Activity Index), lab parameters (biochemistry profile, Malabsorbtion testing, blood count, Bone metabolism relevant hormones and vitamins, inflammatory parameters, Stool analysis, Bone metabolism markers)	—

Measure

Time frame

Questionnaires (Age, weight, height,CD diagnosis date and history, Gender, Current and preceding medications, Comorbidities, Fracture history in 1st degree relatives, Smoking and Alcohol status, Number of flare-ups requiring a visit to the physician and/or corticosteroid use during the preceding year, Lifestyle factors including, history of fractures, BMI, and dietary factors, OSTEO-CHECK and IBDQ-D questionnaire), CDAI (Crohn's Disease Activity Index), lab parameters (biochemistry profile, Malabsorbtion testing, blood count, Bone metabolism relevant hormones and vitamins, inflammatory parameters, Stool analysis, Bone metabolism markers)

—

Countries

Austria

Contacts

Public ContactJohann Bartko

Ludwig Boltzmann-Institut für Osteologie

johann.bartko@osteologie.at+43 (0)1 91021 86924

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026