Influence of a guideline and an additional rapid test for goup A Streptococci on antibiotic prescriptions for patients presenting with sore throat in primary care

Influence of a guideline and an additional rapid test for goup A Streptococci on antibiotic prescriptions for patients presenting with sore throat in primary care - HALS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00013018

Enrollment

570

Registered

2017-11-28

Start date

2010-10-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R07.0 J02.0 J03.0

Interventions

Group 1: Treatment according to the DEGAM guideline 14 "Sore Throat" (2009), see "Background literature" Group 2: Treatment according to a modified version of the DEGAM guideline 14 "Sore Throat": rap

antibiotic prescription only if GAS test is positive Group 3: usual care (routine treatment for patients with sore throat, see also "paper")

Eligibility

Sex/Gender

All

Age

2 Years to No maximum

Inclusion criteria

Inclusion criteria: - First consultation for sore throat =14 days or (f. ex. in young children) the main signs in the pharynx suggesting an infection - patient aged = 2 years - patient moderately or severely affected

Exclusion criteria

Exclusion criteria: - sore throat, but only light impairment - other concurrent illness requring antibiotic treatment - running antibiotic therapy - (suspected) quinzy - (suspected) scarlet fever - history or family history of Acute Rheumatic Fever - consuming disease or suppression of the immune system - insufficent knowledge of the German language

Design outcomes

Primary

Measure	Time frame
rate of antibiotic prescriptions for patients with sore throat as documented by GPs in the consultation questionnaire	—

Secondary

Measure	Time frame
1.Clinical course, as documented by patients in a diary for 10 days (resolution of symptoms [sore throat, fever, feeling ill], impaired daily acitivities, absence from nursery school, school or work), stated as rate of patients per day. 2. Frequency of throat swabs for rapid test and / or culture as documented by GPs in the consultation questionnaire, stated as rates 3. Frequency of GAS in the study population (rate) as found by culture of the study throat swabs of all patients included 4. Frequency of GAS in rapid tests or culture that the GPs initiated themselves (rates) 4. Antibiotics prescribed and duration of therapy as documented by GPs in their questionnaire and by patients in the diary 5. Recommendations to take analgesics (rates) as documented by GPs in their questionnaire 6. Patients‘ perceptions of the consultation concerning their expectations and questions as documented in their questionnaire (Likert scale) 7. Frequency of prescribing an antibiotic to be taken only in case of worsening illness and frequency of them being really taken as documented in the GPs’ questionnaire and in the patients’ diary	—

Measure

Time frame

1.Clinical course, as documented by patients in a diary for 10 days (resolution of symptoms [sore throat, fever, feeling ill], impaired daily acitivities, absence from nursery school, school or work), stated as rate of patients per day. 2. Frequency of throat swabs for rapid test and / or culture as documented by GPs in the consultation questionnaire, stated as rates 3. Frequency of GAS in the study population (rate) as found by culture of the study throat swabs of all patients included 4. Frequency of GAS in rapid tests or culture that the GPs initiated themselves (rates) 4. Antibiotics prescribed and duration of therapy as documented by GPs in their questionnaire and by patients in the diary 5. Recommendations to take analgesics (rates) as documented by GPs in their questionnaire 6. Patients‘ perceptions of the consultation concerning their expectations and questions as documented in their questionnaire (Likert scale) 7. Frequency of prescribing an antibiotic to be taken only in case of worsening illness and frequency of them being really taken as documented in the GPs’ questionnaire and in the patients’ diary

—

Countries

Germany

Contacts

Public ContactHannelore Wächtler

Institut für AllgemeinmedizinChristian-Albrechts-Universität zu Kiel

h.waechtler@allgemeinmedizin.uni-kiel.de49(0)431 50030101

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 11, 2026