Cervical spondylotic myelopathy: Application of spinal diffusion-based microstructural imaging (DMI) and phase-contrast MRI

Conditions

M47.12 G99.2

Marc Hohenhaus, Jan‐Helge Klingler, Christoph Scholz, Florian Volz, Ulrich Hubbe et al. (10 authors)

Neuroradiology2023-06-303 citations

Assessment of spinal cord motion as a new diagnostic MRI-parameter in cervical spinal canal stenosis: study protocol on a prospective longitudinal trial.

Wolf K, Krafft AJ, Egger K, Klingler JH, Hubbe U, Reisert M, Hohenhaus M.

2019-10-129 citations

10.1186/s13018-019-1381-9

Is microdiffusion imaging able to improve the detection of cervical myelopathy? Study protocol of a prospective observational trial (MIDICAM-Trial)

Marc Hohenhaus, Karl Egger, Jan‐Helge Klingler, Ulrich Hubbe, Marco Reisert et al. (6 authors)

BMJ Open2019-09-014 citations

10.1136/bmjopen-2019-029153

Interventions

Group 1: In this propective study we will apply additional new MRI examinations (MDI/PC-MRI) in patients with cervical spondylotic pathologies and possible associated myelopathy to figure out their di

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: a) Symptoms of a radiculopathy od myelopthy induced by cervical degerative disease in combination with a disk herniation or cervical stenosis with contact to the cervical myelon at the MR imaging. b) Age > 18 years c) Informed consent.

Exclusion criteria

Exclusion criteria: a) MRI exclusion criteria b) Patients with prior cervical operations c) Non-degenerative causes for the pathological changings of the cervical spine (tumor, infection/inflammation, tramatic injuries) d) severe internistic pathologies e) severe neurologic or psychiatric diseases, e.g. dementia, Parkinson's disease, Multiple sclerosis, CNS inflammation, Depression, Schizophrenia

Design outcomes

Primary

Measure	Time frame
Sensitivity and specifity of the MIDI concerning functional (clinical or electrophysiological) or abstinent myelopathy.	—

Secondary

Measure	Time frame
Pathologic changings in the MIDI compared to conventional MRI diagnostics in cervical myelopathy patients. Development of clinical, electrophysiological and conventional MRI changings in initial pathological altered MIDI.	—

Countries

Germany

Contacts

Public ContactMarc Hohenhaus

Klinik für Neurochirurgie, Universitätsklinikum Freiburg

marc.hohenhaus@uniklinik-freiburg.de076127050010

Outcome results

None listed