PIPE: Physiotherapeutic intervention with Pelvic Floor Muscle Training (PFMT) for Treatment of Low Anterior Resection Syndrome (LARS)

PIPE: Physiotherapeutic intervention with Pelvic Floor Muscle Training (PFMT) for Treatment of Low Anterior Resection Syndrome (LARS) - PIPE

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00012932

Enrollment

142

Registered

2017-09-22

Start date

2018-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C20 R15

Interventions

Group 1: Intervention Group: pelvic floor muscle Training by specialized physiotherapists for 3 months in 12 sessions with approximately 20 minutes. Group 2: control group: no pelvic floor muscle tra

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age > 18 years, TME surgery, histologically confirmed rectal cancer (= 12 cm from anal verge), informed consent, stoma closure.

Exclusion criteria

Exclusion criteria: severe untreated physical or mental impairment, lack of compliance with the trial procedure, present chemotherapy.

Design outcomes

Primary

Measure	Time frame
The primary endpoint is absolute change to baseline of LARS score (Low Anterior Resection Syndrome) 12 weeks after commencement of PFMT (Pelvic Floor Muscle Training). The LARS score evaluates bowel dysfunction.	—

Secondary

Measure	Time frame
The secondary objectives are absolute changes to baseline of LARS (Low Anterior Resection Syndrome) score 6, 18 and 24 weeks and of QLQ-C30 score (Quality of Life Questionnaire) 6, 12, 18 and 24 weeks after commencement of PFMT (Pelvic Floor Muscle Training)	—

Countries

Germany

Contacts

Public ContactJonas Schiemer

Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz

jonasfriedrich.schiemer@unimedizin-mainz.de06131 170

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026