L40.0 M07.00
Conditions
Interventions
Group 1: 25 patients with psoriasis vulgaris will be examined by nailfold capillaroscopy to evaluate the frequency, the extent, and the morphological patterns of changes in nailfold capillaries
Grou
Sponsors
Universitäts-Hautklinik Heidelberg
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Moderate to severe psoriasis vulgaris and/or Psoriasis arthritis for at least 6 months. Signed written informed consent.
Exclusion criteria
Exclusion criteria: Patients under current exposure to any anti-psoriatic systemic therapy. Active ongoing inflammatory diseases. Patients that are unable to give informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective of this study is to investigate nailfold capillary patterns in 50 patients with psoriasis vulgaris alone or accompanying psoriasis arthritis compared to 25 healthy subjects. The changes will be evaluated only one time by means of nailfold capillaroscopy at the baseline visit. | — |
Secondary
| Measure | Time frame |
|---|---|
| A secondary objective of this study is to analyze the impact of the psoriasis area and severity score (PASI), nail psoriasis and demographic and clinical data e.g. age, gender, duration of the disease, manifest cardiovascular disease on nailfold capillaroscopy patterns. Date will be retrieved during the baseline visit. | — |
Countries
Germany
Contacts
Public ContactHolger Haenssle
Universitäts-Hautklinik Heidelberg
Outcome results
None listed