F32.1 F32.2
Conditions
Interventions
Group 1: 30 inpatients with depressive episode: To quantify autonomic modulation the cardiovascular signals (e.g. heart rate, blood pressure) will be observed in various situations (relaxed or active)
Sponsors
Klinik für Psychiatrie und Psychotherapie Universitätsklinik der Paracelsus Medizinischen Privatuniversität
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Diagnosis of F32.1 (moderate depressive episode) or F32.2 (severe depressive Episode without psychotic symptoms, inpatient-care for at least 3 weeks, Age between 18 and 65, ability to give one's consent
Exclusion criteria
Exclusion criteria: Diseases of the cardiovascular or autonomic nervous system
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Baroreflex sensitivity, monitored (on the first day of inpatient care and after three weeks) and calculated during both autonomic testings. Baroreflex sensitivity can be calculated if both blood pressure and heart rate are recorded simultaneously. Sequences of simultaneous drop in blood pressure and raise in heart rate or vice versa are detected. The slope of the regression line of change in heart rate and blood pressure equals the baroreflex sensitivity. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the severity of depressive symptoms, measured by self Rating (Beck Depression Inventory) and health professional Rating (Hamilton Rating Scale for Depression) on the first day of inpatient care and after three weeks. | — |
Countries
Germany
Contacts
Public ContactLennard Geiß
Klinik für Psychiatrie und Psychotherapie Universitätsklinik der Paracelsus Medizinischen Privatuniversität
Outcome results
None listed