Short-term, long-term and cost-effectiveness of treating depression and anxiety disorders in children and adolescents – a randomized controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00012823

Enrollment

420

Registered

2017-09-27

Start date

2018-07-26

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression and/or anxiety disorder F30-F39 F40 F41 F42

Interventions

Group 1: outpatient psychodynamic psychothrapy in single patient setting, therapy frequnency and duration depend on indication Group 2: oupatient cognitive behavioral therapy in single patient settin

Eligibility

Sex/Gender

All

Age

6 Years to 18 Years

Inclusion criteria

Inclusion criteria: diagnosis of a depressive disorder (ICD-10; F30-F39) or an anxiety disorder (ICD-10; F40-F42) informed consent (patients and parents)

Exclusion criteria

Exclusion criteria: psychotic disorders, eating disorders, substance use related disorders (except caffeine and nicotine), autism spectrum disorders, mutism, personality disorders neurologic disorders severe mental retardation (filling out questionnaires and interview are not feasible) low command of the german language

Design outcomes

Primary

Measure	Time frame
Number of psychiatric diagnoses respectively number of diagnostic criteria will be assessed by Kiddie-SADS interview (Delmo et al., 2001). The Kiddie-SADS interview will be conducted by a trained rater external to the project before treatment henceforth annually over a 5 year period for each child.	—

Secondary

Measure	Time frame
Children´s depressive symptomatology will be assessed by children´s (aged 10 years and older) and parents´ rating of the german version of the "Children´s depression inventory" (Depressionsinventar für Kinder und Jugendliche (DIKJ; Stiensmeier-Pelster, Schürmann, & Duda, 2000) before therapy starts and henceforth annually over a five year period. Children´s anxiety symptomatology will be assessed by children´s (aged 10 years and older) and parents´ rating of the german version of the "Screen for child anxiety related emotional disorders" (Scared; Birmaher, Khetarpal, Cully, Brent, & McCanzie, 1995) before therapy starts and henceforth annually over a five year period. Cildren´s psychiatric disorders will further be assessed by parents´ rating of the german version of the "Child behavior checklist" (CBCL; Achenbach, 1991) before therapy starts and henceforth annually over a five year period. Cildren´s psychiatric disorders will further be assessed by children´s (aged 10 years and older) rating of the german version of the "Youth self report" (YSR; Achenbach, 1991) before therapy starts and henceforth annually over a five year period. Children´s structural functioning will be assessed by self-report (children and adolescents aged 10 years and older) using the german structure questionnaire for the "Operationalized psychodynamic diagnostic for children and adolescents" (OPD-KJ2-SF, Schrobildgen et al., 2017) before therapy starts and henceforth annually over a five year period. Children´s health related quality of life will be assessed by children´s (aged 10 years and older) and parents´ rating of the german version of the Kidscreen (Ravens-Sieberer & the European KIDSCREEN group, 2006) before therapy starts and henceforth annually over a five year period. Children´s global impairment will be assessed by a trained rater external to the project using the german "Skala zur Gesamtbeurteilung von Kindern und Jugendlichen" (SGKJ; Steinhausen, 1985) before therapy starts an	—

Measure

Time frame

Children´s depressive symptomatology will be assessed by children´s (aged 10 years and older) and parents´ rating of the german version of the "Children´s depression inventory" (Depressionsinventar für Kinder und Jugendliche (DIKJ; Stiensmeier-Pelster, Schürmann, & Duda, 2000) before therapy starts and henceforth annually over a five year period. Children´s anxiety symptomatology will be assessed by children´s (aged 10 years and older) and parents´ rating of the german version of the "Screen for child anxiety related emotional disorders" (Scared; Birmaher, Khetarpal, Cully, Brent, & McCanzie, 1995) before therapy starts and henceforth annually over a five year period. Cildren´s psychiatric disorders will further be assessed by parents´ rating of the german version of the "Child behavior checklist" (CBCL; Achenbach, 1991) before therapy starts and henceforth annually over a five year period. Cildren´s psychiatric disorders will further be assessed by children´s (aged 10 years and older) rating of the german version of the "Youth self report" (YSR; Achenbach, 1991) before therapy starts and henceforth annually over a five year period. Children´s structural functioning will be assessed by self-report (children and adolescents aged 10 years and older) using the german structure questionnaire for the "Operationalized psychodynamic diagnostic for children and adolescents" (OPD-KJ2-SF, Schrobildgen et al., 2017) before therapy starts and henceforth annually over a five year period. Children´s health related quality of life will be assessed by children´s (aged 10 years and older) and parents´ rating of the german version of the Kidscreen (Ravens-Sieberer & the European KIDSCREEN group, 2006) before therapy starts and henceforth annually over a five year period. Children´s global impairment will be assessed by a trained rater external to the project using the german "Skala zur Gesamtbeurteilung von Kindern und Jugendlichen" (SGKJ; Steinhausen, 1985) before therapy starts an

—

Countries

Germany

Contacts

Public ContactSilke Wiegand-Grefe

Universitätsklinikum Hamburg-Eppendorf

s.wiegand-grefe@uke.de040 - 741053603

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026