Evoked Potentials after Painful Cutaneous Electrical Stimulation Depict Pain Relief during a Conditioned Pain Modulation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00012779

Enrollment

Registered

2017-07-24

Start date

2015-07-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

Group 1: We examine the influcence of contralateral applied painful cold water (10°C) on PCES-EPs (Cortical evoked potentials) and PCES (=painful cutaneous electrical stimulation)-induced pain in heal

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Healthy subjects, age>18 years, given written informed consent

Exclusion criteria

Exclusion criteria: Current pain, neuropathy, nerve lesions, topical drug treatment, history of neurological, psychiatric or severe cardiovascular diseases

Design outcomes

Primary

Measure	Time frame
Primary outcome of this trial is the reduction of PCES-EP induced by painful cold water. Therefore, we assessed the ratio of the amplitude of PCES-EP before and during conditioning cold water.	—

Secondary

Measure	Time frame
As secondary outcome parameter, we assessed the relief of PCES induced pain using a 101-point numerical rating scale before and during conditioning cold water as a ratio.	—

Countries

Germany

Contacts

Public ContactOliver Höffken

Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH

oliver.hoeffken@bergmannsheil.de00492343020

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 9, 2026