ECCO2R and NIV-NAVA in severe acute exacerbation of COPD

ECCO2R and NIV-NAVA in severe acute exacerbation of COPD - ECCO2R and NIV-NAVA in AECOPD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00012737

Enrollment

Registered

2017-07-20

Start date

2015-10-04

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J44.9 J46

Interventions

Group 1: Patients with severe acute exacerbation COPD requiering extracorporeal CO2 elimination and NIV NAVA will be examined during weaning from extracorporeal CO2 elimination. All patients are at le

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: • acute exacerbation of asthma or COPD, requiring extracorporeal CO2 elimination and NIV-NAVA due to severe respiratory acidosis • Placement of NAVA probe and ECCO2R feasible

Exclusion criteria

Exclusion criteria: - Pregnancy - Age 75 Y - Severe contraindications against Anticoagulation - Severe contraindications against non-invasive ventilation

Design outcomes

Primary

Measure	Time frame
Measurement of ventilatory response to reduced extracorporeal CO2 elimination	—

Secondary

Measure	Time frame
- electrical activity of the diaphragm - CO2 in arterial blood gas analysis - Patient reported dyspnoea	—

Countries

Germany

Contacts

Public ContactChristrian Karagiannidis

Lungenklinik Köln-Merheim

Karagiannidisc@kliniken-koeln.de0221-890718809

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026