Hemianopia in children: evaluation of adaptive mechanisms as a basis for rehabilitation and for analysis of structure-function relations for the prediction and control of visual functions in brain surgery

Hemianopia in children: evaluation of adaptive mechanisms as a basis for rehabilitation and for analysis of structure-function relations for the prediction and control of visual functions in brain surgery - HeKiRe

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00012695

Enrollment

Registered

2017-07-18

Start date

2014-10-22

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H53.4

Interventions

Group 1: All children train at home on their computer with a saccadic training software, which was specially developed for children. The saccadic training consists of search tasks with symbols suitabl

Eligibility

Sex/Gender

All

Age

6 Years to 19 Years

Inclusion criteria

Inclusion criteria: Age between 6-19; Presence of MRI findings; Suspected or definitive diagnosis of homonymous hemianopia oder quadrantanopia; Consent from at least one parent

Exclusion criteria

Exclusion criteria: Inadequate cooperation

Design outcomes

Primary

Measure	Time frame
1.Establishment of structure-function relationships between lesions of visual pathway and / or visual cortex and visual field loss by means of evaluation of MRI images at initial examination. 2. To assess adaptive mechanisms in children with hemianopia before training (T1), directly after training (T2) and 6 weeks after end of training (T3): a) Neuro-ophthalmological examination at T1 b) examination of the visual field at T1 c) Measurement of search times during saccadic training by the Software at start and end of training (between T1 and T2) d) Measurement of search times during infrared eye tracking, free viewing and search tasks at T1, T2 and T3. e) Measurement of search times in the "Table Test", in which search tasks with real objects are performed on a table at T1, T2 and T3 f) Quality of life Questionnaires: KINDL®, IVI_C, CVAQC-25 at T1, T2 and T3 3. Another aim of the study is the development and evaluation of a saccadic training program for children with hemianopia before and during the training 4. A further aim is not only to investigate children with long-lasting hemianopia, but also to investigate children with acute-induced hemianopia (in the context of epilepsy-surgical procedures or after tumor surgery) to assess the time course of the visual field loss and the development of compensatory mechanisms. PS: due to a small number of patients in point 4, this point will be further examinated in a follow-up study.	—

Measure

Time frame

1.Establishment of structure-function relationships between lesions of visual pathway and / or visual cortex and visual field loss by means of evaluation of MRI images at initial examination. 2. To assess adaptive mechanisms in children with hemianopia before training (T1), directly after training (T2) and 6 weeks after end of training (T3): a) Neuro-ophthalmological examination at T1 b) examination of the visual field at T1 c) Measurement of search times during saccadic training by the Software at start and end of training (between T1 and T2) d) Measurement of search times during infrared eye tracking, free viewing and search tasks at T1, T2 and T3. e) Measurement of search times in the "Table Test", in which search tasks with real objects are performed on a table at T1, T2 and T3 f) Quality of life Questionnaires: KINDL®, IVI_C, CVAQC-25 at T1, T2 and T3 3. Another aim of the study is the development and evaluation of a saccadic training program for children with hemianopia before and during the training 4. A further aim is not only to investigate children with long-lasting hemianopia, but also to investigate children with acute-induced hemianopia (in the context of epilepsy-surgical procedures or after tumor surgery) to assess the time course of the visual field loss and the development of compensatory mechanisms. PS: due to a small number of patients in point 4, this point will be further examinated in a follow-up study.

—

Countries

Germany

Contacts

Public ContactSusanne Trauzettel-Klosinski

Forschungseinheit für Visuelle Rehabilitation,Department für Augenheilkunde,Universitäsklinikum Tübingen

susanne.trauzettel-klosinski@uni-tuebingen.de+49-(0)7071-29-84831

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026