G20 G25
Conditions
Interventions
Group 1: Monopolar stimulation:
each patient will be programmed consecutively and in a randomized order in the following different stimulation-settings: monopolar stimulation, conventional bipolar sti
Sponsors
Universitätsklinikum Köln
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: - Diagnosis of essential tremor or tremordominant Parkinson's disease - Implantation of DBS-electrodes in the Ventral intermediate nucleus thalami (VIM) for at least 3 months - Age between 18 and 80 years - Full understanding of all study related procedures and ability to sign the written informed consent
Exclusion criteria
Exclusion criteria: - no withdrawal of medication over night possible - dementia or other relevant cognitive impairment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of side-effect thresholds between 1. monopolar, 2. conventional bipolar, and 3. directional bipolar stimulation. Prim. Outcome: immediate treshold (in mA) of side effects in the different stimulation settings during a monopolar review | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of effect on tremor of 1. monopolar, 2. conventional bipolar, and 3. directional bipolar stimulation. Sec. Outcome: Tremor Rating Scale Total Score of patient when stimulating just below the treshold of side effects, 15 minutes after the stimulation ist programmed | — |
Countries
Germany
Contacts
Public ContactJulia K. Steffen
Klinik und Poliklinik für Neurologie, Uniklinik Köln
Outcome results
None listed