3D-Geometry, dynamics and flow dynamics of the left atrial appendage for risk stratification of thrombembolic events.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00012637

Enrollment

Registered

2017-09-04

Start date

2017-09-18

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I63 I48

Interventions

Group 1: This study aims at understanding the effect of the left atrial appendage (LAA) on the occurrence of thromboembolic events in humans. Parameters investigated are the LAA-volume, the LAA shape,

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with ischemic stroke and neurological symptoms due to a thrombembolic source (scattered infarction) and patients without stroke who get a TEE for other medical reasons

Exclusion criteria

Exclusion criteria: children, persons who are not competent to give consent, contraindications for trans-esophageal echo, allergy to contrast agent

Design outcomes

Primary

Measure	Time frame
This study aims at understanding the effect of the left atrial appendage (LAA) on the occurrence of thromboembolic events in humans. Parameters investigated are the LAA-volume, the LAA shape, and the two and three dimensional velocity components of the blood flow inside the LAA and the left atrium. Those parameters are obtained by trans-esophageal echo (TEE) with and without an ultrasound contrast agent and are compared between both groups.	—

Measure

Time frame

This study aims at understanding the effect of the left atrial appendage (LAA) on the occurrence of thromboembolic events in humans. Parameters investigated are the LAA-volume, the LAA shape, and the two and three dimensional velocity components of the blood flow inside the LAA and the left atrium. Those parameters are obtained by trans-esophageal echo (TEE) with and without an ultrasound contrast agent and are compared between both groups.

—

Countries

Germany

Contacts

Public ContactMario Kasner

Klinik für Kardiologie, Campus Benjamin Franklin, Charite Universitätsmedizin Berlin

mario.kasner@charite.de030450513774

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026