E11
Conditions
Interventions
Group 1: 2.5 g cocoa, encapsulated (5 capsules à 0.5 g), ingested with breakfast, at least 2 weeks washout between ingestion of cocoa and placebo capsules
Group 2: 2.5 g microcrystalline cellulose, e
for further details see arm 1
Sponsors
Hochschule NiederrheinFachbereich Oecotrophologie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Type 2 diabetes mellitus with dietetic or pharmacological treatment, duration of diabetes (after diagnosis) at least 1 year, stable metabolic control (HbA1c between 6.5 – 7.5% with consideration of individual therapeutic aims), hypertension, overweight/obesity according to the weight classifications of the WHO, non-smoker for at least 3 months, written informed consent
Exclusion criteria
Exclusion criteria: Insulin therapy, known gastrointestinal diseases accompanied by diarrhea or malabsorption, cardiac pacemaker and other implanted automatically electronic tools, known or planned pregnancy, allergy to hazelnuts, large consumption of chocolate (> 100 g/day), red wine (> 1 glass/day), cocoa drink, green and black tea (> 1 cup/day), regular supplementation of vitamin preparations, intake of flavanol-rich supplements
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure (systolic, diastolic): Investigation at both study days before and 2 and 4 h after breakfast with capsules intake | — |
Secondary
| Measure | Time frame |
|---|---|
| Glucose, insulin, triglycerides, cholesterol (total, LDL, HDL): Investigation at both study days before and 2 and 4 h after breakfast with capsules intake | — |
Countries
Germany
Contacts
Public ContactNorbert;Janina Ludwig;Rynarzewski
Gemeinschaftspraxis Prof. Dr. Ludwig & Dr. Honl;Hochschule NiederrheinFachbereich Oecotrophologie
Outcome results
None listed