Taste disorders during chemotherapy - TASTE Trial - Effectivity of a taste and smell training and structured, individual intervention program to improve taste perception of patients undergoing chemotherapy

Taste disorders during chemotherapy - TASTE Trial - Effectivity of a taste and smell training and structured, individual intervention program to improve taste perception of patients undergoing chemotherapy - TASTE Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00012501

Enrollment

Registered

2019-02-01

Start date

2017-04-14

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C00-C97

Interventions

Group 1: About 2 out of 3 cancer patients report a restriction or lack of taste. These disorders can occur as an acute side effect undergoing therapy or many years later as a long-term effect. A restr

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - patients undergoing chemotherapy (tumor localisation: breast, lung, esophagus, pancreas, stomach and intestine) - age = 18 years - prior written consent

Exclusion criteria

Exclusion criteria: - presence of a genetic metabolic disorder - treatment/ previous treatment of an eating disorder (anorexia, bulimia, binge eating) - parenteral nutrition or supplemental enteral nutrition (food via PEG or PEJ, high calorie drinking food such as Fresubin or Fortimel) undergoing therapy for tumor cachexia - irradiation in the head/ neck area - pregnancy

Design outcomes

Primary

Measure	Time frame
The primary endpoint is the improvement of objective taste by clinically relevant 2 taste strip points in at least 50% of the patients of the intervention group	—

Secondary

Measure	Time frame
- Improvement of the objective taste category "salty", "sweet", "sour" and "bitter" (measured by taste strip) - Improvement of subjective taste perception (measured by anamnesis sheet of Prof. T. Hummel) - Feasibility and acceptance of taste and smell training - Recording the quality of life of all study patients	—

Countries

Germany

Contacts

Public ContactJulia von Grundherr

Universitäres Cancer Center Hamburg (UCCH)Hubertus Wald Tumorzentrum

j.von-grundherr@uke.de+49 (0) 40 7410 - 51845

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026