I63 I64 I50
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Ischemic stroke according to the WHO definition (Hatano 1976) or the corresponding lesion in cerebral imaging irrespective of the duration of the symptoms, maximum 3 days before inclusion with (cases) vs. without involvement (control) of the insular cortex In screening by handheld or routine echocardiography free of systolic dysfunction Written consent of the patient or written consent of the legal representative or relative is available Sufficient German language skills
Exclusion criteria
Exclusion criteria: The exclusion criterion is the inclusion of the patient in an acute intervention / AMG study in order to monitor the natural course of cardiovascular diseases as well as comorbidities Patients who were initially diagnosed with a stroke but who were subsequently diagnosed with a different diagnosis Systolic dysfunction in screening Lack of readiness / ability to perform follow-up appointments
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is the development of new systolic dysfunction in ischemic cerebral infarction patients with involvement of the insular cortex within the first three months after index event. | — |
Secondary
| Measure | Time frame |
|---|---|
| Identification of comorbidities (rehospitalisation rate, degree of independence, cognition, depression, anxiety) after 3 months, that are associated with development of a new systolic dysfunktion within the first three months after ischemic stroke Cases and controls are compared by means of echocardiographic and clinical exams, blood based biomarkers, interviews about comorbidities, medication and risk factors after 1 week as well as 4 and 12 weeks. | — |
Countries
Germany
Contacts
Institut für Klinische Epidemiologie und Biometrie Würzburg