Clinical trial for investigating social cognition in healthy participants and patients with either mild cognitive disorder or alzheimer disease.

Clinical trial for investigating social cognition in healthy participants and patients with either mild cognitive disorder or alzheimer disease. - Social Cognition

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00012441

Enrollment

120

Registered

2017-06-06

Start date

2017-05-19

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F00.9 F06.7

Interventions

Group 1: Every arm: some tests including video material, questionnaires and photographies

the investigation lasts 1,5 hours and takes place in the center for memory disorders or at the patients home. Arm1: Patients with alzheimer disease Group 2: Patients with mild cognitive impairment G

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria patients: - diagnosed amnestic MCI or alzheimer disease (criterias following the S3-dementia-guideline) - MCI-patients: detailed neuropsychological Investigation within the last 12 month - elaborate explanatory meeting and written agreement - Age: older than 50 years - good knowledge of german language - Minimum 6 years of education or the equivalent of alphabetisation Inclusion criteria controlgroup: - unimpaired social cognition - elaborate explanatory meeting and written agreement - Age: 20 - 35 years or older than 50 years - good knowledge of german language - Minimum 6 years of education or the equivalent of alphabetisation

Exclusion criteria

Exclusion criteria: Exclusion criteria patients: - urgent psychological or neurological diseases (clinical relevant episode of depression, geriatric depression scale, scoring 11 Points or higher) Exclusion criteria controlgroup: - dementia or mild cognitive impairment - ability of social cognition under the range according to age, gender and education urgent psychological or neurological diseases (clinical relevant episode of depression, geriatric depression scale, scoring 11 Points or higher or BDI I-II > 20 points)

Design outcomes

Primary

Measure	Time frame
Social cognition, investigated with the following tests: The Karolinska directed emotional faces (KDEF): 28 Pictures of male and female faces showing the Basic emotions; decoding emotions Reading mind in the eyes-test: 36 Pictures of male and female eyes; Decoding emotions MASC (Movie for the Assessment of Social Cognition): Video material and following questionnaire; theory of mind Theory of mind Picture Stories Task: Sorting 6 picture stories in the right order and following questionnaire	—

Measure

Time frame

Social cognition, investigated with the following tests: The Karolinska directed emotional faces (KDEF): 28 Pictures of male and female faces showing the Basic emotions; decoding emotions Reading mind in the eyes-test: 36 Pictures of male and female eyes; Decoding emotions MASC (Movie for the Assessment of Social Cognition): Video material and following questionnaire; theory of mind Theory of mind Picture Stories Task: Sorting 6 picture stories in the right order and following questionnaire

—

Secondary

Measure	Time frame
Cognitive measures (MMST, CERAD)	—

Countries

Germany

Contacts

Public ContactAnn-Katrin Schild

Klinik und Poliklinik für Psychiatrie und Psychotherapie; Zentrum für Gedächtnisstörungen (ZfG)/ Center for memory disorders; Universitätsklinikum Köln

ann-katrin.schild@uk-koeln.de+49 221 478-32298

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026