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Acute Effects of Blood Flow Restriction on Exercise-Induced Free Radical Production in Young and Healthy Subjecty: A Randomized Controlled Trial

Acute Effects of Blood Flow Restriction on Exercise-Induced Free Radical Production in Young and Healthy Subjecty: A Randomized Controlled Trial - BFR-ROS Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00012439
Enrollment
15
Registered
2017-07-24
Start date
2017-01-09
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy subjects

Interventions

Group 1: low-intensity exercise with blood flow restriction (LIBR)
intensity: 30% 1RM
repetitions: 30-15-15-15
interset rest period: 30 sec Group 2: low-intensity exercise without blood flow restriction (LI)
interset rest period: 30 sec Group 3: high-intensity exercise without blood flow restriction (HI)
intensity: 80% 1RM
repetitions: 10-10-10
interset rest period: 2 min Group 4: rest with blood flow restriction (BR)

Sponsors

Institut für Sport und Sportwissenschaft, Albert-Ludwigs-Universität Freiburg
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: - male - age: 18 - 30 years - resistance training experience: > 1 year

Exclusion criteria

Exclusion criteria: - smoking - hypertension (BP > 139/89 mmHg) - deep vein thrombosis or history of thrombosis in the family - chronic illness

Design outcomes

Primary

MeasureTime frame
Ex vivo free radical production measured with electron paramagnetic resonance technique immediately before and after the training session—

Secondary

MeasureTime frame
metabolic parameters in capillary blood and ratings of perceived exertion (BORG scale) measured immediately before and after the training session—

Countries

Germany

Contacts

Public ContactChristoph Centner

Albert-Ludwigs-Universität Freiburg

christoph.centner@sport.uni-freiburg.de+4917632850883

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026