healthy subjects
Conditions
Interventions
Group 1: In Arm 1 only helathy patients with a Gingivitis are included.
In the first patient session the patients get a check, survey of dental indices is conducted, recording and explaining the study
Sponsors
Zahnklinik Uniklinik Köln
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Patients who regularly (every 6 months) get a dental checkup in the dental clinic of the University Hospital of Cologne - Patients who belong to the dental clinic's recallsystem and receive a professional teeth cleaning every six months - Patients who have no diseases - Patients who have accepted the declaration of agreement and dont take part in another study - Patients who are older than 18 years
Exclusion criteria
Exclusion criteria: - Patients who are generally not indicated for dental treatment - Patients who are regularly take antibiotics - Patients, for who a experimental bacteremia could be a risk, especially pregnant women or immunosuppressed patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| An orally induced bacteremia is measured after brushing (after 30 seconds). For this purpose, the oral microbiom of the saliva is measured by means of a dorsal tongue smear before brushing the teeth. This is then compared with the microbiom of the blood after brushing. A blood sampling is carried out after brushing the teeth. | — |
Secondary
| Measure | Time frame |
|---|---|
| The microbiom in the blood, triggered by bacteremia by brushing, correlates with the oral microbiome of a dorsal tongue swab. | — |
Countries
Germany
Contacts
Public ContactKarolin Höfer
Zahnklinik Uni Köln
Outcome results
None listed