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Analysis of the Voice in Patients with Essential Tremor (ET) and Deep Brain Stimulation (DBS): an electroglottography study

Analysis of the Voice in Patients with Essential Tremor (ET) and Deep Brain Stimulation (DBS): an electroglottography study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00012379
Enrollment
40
Registered
2017-07-31
Start date
2017-05-05
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stimulation induced dysarthria G25.0

Interventions

Group 1: Patient group
Recording of vibration of the vocal folds via noninvasive Electroglottography (EGG), Recording of a Tremor Rating Scale (TRS) video, Questionnaires concerning the patients tremor
all tasks/analyses will be done in stimulation-ON- and stimulation-OFF-state with a 15-minute break inbetween
the stimulation-ON and -OFF-state will be analysed in a randomised order Group 2: Control group (healthy volunteers)
Recording of vibration of the vocal folds via noninvasive Electroglottography (EGG)

Sponsors

Universitätsklinikum Köln
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients, male or female, with Essential Tremor and DBS in the Ventral intermediate nucleus thalami (VIM) Patients have to be between 18 and 80 years of age Patients have to be german native speakers Patients must be capable to give their informed consent and must agree to the study

Exclusion criteria

Exclusion criteria: Disease that could influence the voice besides Essential Tremor Patients were implanted with DBS-device during the last three months

Design outcomes

Primary

MeasureTime frame
The effect of Deep Brain Stimulation of the nucleus ventralis intermedius on motor control of the lanynx in patients with essential tremor. We measure and analyse vocal fold vibrations by means of Electroglottography in both stimulation-ON and stimulation-OFF conditions.

Secondary

MeasureTime frame
The effect of Deep Brain Stimulation of the nucleus ventralis intermedius on tremor in patients with essential tremor. We measure and analyse tremor by means of the Tremor Rating Scale in both stimulation-ON and stimulation-OFF conditions.

Countries

Germany

Contacts

Public ContactJulia K. Steffen

Klinik und Poliklinik für Neurologie, Uniklinik Köln

julia.steffen@uk-koeln.de+492214784013

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026