the state of the athletic performance and the nutritional status of healthy endurance athletes will be investigated
Conditions
Interventions
Group 1: It is a cross-sectional study in the form of a pilot project. The study includes a sport-medical examination in which the athletic performance of the subjects is determined. In addition, a nu
Sponsors
Institut für Lebensmittelwissenschaft und Humanernährung
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: - healthy, competent men and women aged 18-35 years - stable weight since min. 6 months (±3 kg), BMI 18,5-25 kg/m2 - endurance athlete since min. 6 months, who trains 3 to 5 times a week - same nutritional diet since 6 months
Exclusion criteria
Exclusion criteria: - acute febrile infections - severe chronic diseases (cancer, diabetes type 1, manifest cardiovascular disease, renal insufficiency, liver disease) - chronic diseases of the gastrointestinal tract (ulcerative colitis, Crohn's disease, pancreatic insufficiency) - Nutrient intolerances (eg celiac disease, lactose intolerance) - known endocrine and immunological disorders - regular intake of laxatives - addiction to alcohol/drugs - any illness which, at the discretion of the doctor, excludes any physical strain - non-consentable subjects - participation in another clinical trial or participation within the past 30 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • Maximum physical performance in watts / kg body weight, by stage test on a bicycle Ergometer; one-time survey, cross-sectional study | — |
Secondary
| Measure | Time frame |
|---|---|
| • Max. physical performance in watts / kg fat-free mass • Lactate concentration during the physical stress test • Parameters of glucose metabolism (fasting glucose, insulin, HbA1c, HOMA) • Parameters of fat metabolism (LDL, HDL, TC, TG) • albumin, total protein • Potassium, calcium, magnesium • Folic acid, zinc • Parameters of the iron metabolism (iron, transferrin, ferritin) • Vitamin B12 in serum, HoloTC, homocysteine in plasma, methylmalonic acid (MMA) in serum • Calcidiol in the serum • Omega-3 index of erythrozytes one-time survey, cross-sectional study •Oxylipins: - AA metabolites: 6-keto-PGF1a, 20-COOH-LTB4, 20-OH-LTB4, TXB2, LXA4, 11,12-,15-TriHETrE, PGF2a, PGE2, PGD2, PGJ2, PGB2, 15-deoxy-PGJ2, 6-trans-LTB4, LTB5, LTB4, LTB3, 5-HETE, 8-HETE, 9-HETE, 11-HETE, 12-HETE, 15-HETE, 20-HETE, 5-oxo-ETE, 15-oxo-ETE, 5(6)-EpETrE, 8(9)-EpETrE, 11(12)-EpETrE, 14(15)-EpETrE, 5,6-DiHETrE, 8,9-DiHETrE, 11,12-DiHETrE, 14,15-DiHETrE - EPA metabolites: Resolvin E1, PGE3, PGD3, 5-HEPE, 8-HEPE, 12-HEPE, 15-HEPE, 8(9)-EpETE, 11(12)-EpETE, 14(15)-EpETE, 17(18)-EpETE, 5,6-DiHETE, 5,15-DiHETE, 8,9-DiHETE, 8,15-DiHETE, 11,12-DiHETE, 14,15-DiHETE, 17,18-DiHETE - DHA metabolites: 4-HDHE, 7-HDHE, 8-HDHE, 10-HDHE, 11-HDHE, 13-HDHE, 14-HDHE, 16-HDHE, 17-HDHE, 20-HDHE, 22-HDHE, 10(11)-EpDPE, 13(14)-EpDPE, 16(17)-EpDPE, 19(20)-EpDPE, 4,5-DiHDPE, 7,8-DiHDPE, 10,11-DiHDPE, 13,14-DiHDPE, 16,17-DiHDPE, 19,20-DiHDPE - LA metabolites: THF diol, EKODE, 13-HODE, 9-HODE, 13-oxo-ODE, 9-oxo-ODE, 9,10-DiHOME, 12,13-DiHOME, 9(10)-EpOME, 12(13)-EpOME, 9,12,13-TriHOME, 9,10,13-TriHOME - DGLA metabolites: 15(S)-HETrE, PGE1, PGD1 - ALA metabolites: 9-HOTrE, 13-HOTrE, 9(10)-EpODE, 12(13)-EpODE, 15(16)-EpODE, 9,10-DiHODE, 12,13-DiHODE, 15,16-DiHODE - sirtuin 1,3,4,5 - parameters of oxidative stress (MDA, nitrate, nitrite) - amino acid profile | — |
Countries
Germany
Contacts
Public ContactJosefine Nebl
Insitut für Lebensmittelwissenschaft und Humanernährung
Outcome results
None listed