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Pilot study to reduce anticholinergic load

Pilot study to reduce anticholinergic load

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00012346
Enrollment
20
Registered
2017-05-02
Start date
2017-05-11
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug therapy safety

Interventions

Group 1: The decision aid provided by a study team member will be analysed descriptively via the phycisians’ written feedback. Additionally, the anticholinergic load of patients taking at least one a

Sponsors

Abteilung Klinische Pharmakologie und Pharmakoepidemiologie, Medizinische Klinik
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: Patient admitted to the Geriatric Rehabilitation of the Agaplesion Bethanien Hospital in Heidelberg; Age = 65 years; Taking at least one strong anticholinergic drug on a regular basis (this condition does not affect the comparison group); cognitive and physical stable to participate in the study

Exclusion criteria

Exclusion criteria: Mental or physical condition which does not allow the study participation; Particularly, patients with stroke, postoperative delirium, or dementia are excluded; Missing informed consent

Design outcomes

Primary

MeasureTime frame
Development and testing of different models for predicting anticholinergic load (time point of analysis: study end); Examination of the practicability of the decision aid for reducing anticholinergic load via feedback questionnaires of the participating physicians (time point of examination: during study).

Secondary

MeasureTime frame
Characterization of patients with different anticholinergic loads by cognition tests as well as by the assessment of anticholinergic adverse drug reactions at admission and approximately 14 days later (time of examination: during study).

Countries

Germany

Contacts

Public ContactTanja Mayer

Abteilung Klinische Pharmakologie und Pharmakoepidemiologie, Medizinische Klinik

tanja.mayer@med.uni-heidelberg.de0049(0)6221/5634325

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026