Volitional Modification of Brain Activity in ASD

Conditions

F84.5 F84.1

Gabriel Anton Auer, Paul L. Plener, Luise Poustka, Lilian Konicar

Child and Adolescent Psychiatry and Mental Health2025-05-19

Individual brain regulation as learned via neurofeedback is related to affective changes in adolescents with autism spectrum disorder

Manfred Klöbl, Karin Prillinger, Robert Diehm, Kamer Doganay, Rupert Lanzenberger et al. (8 authors)

Child and Adolescent Psychiatry and Mental Health2023-01-129 citations

10.1186/s13034-022-00549-9

Impulsivity Moderates the Effect of Neurofeedback Training on the Contingent Negative Variation in Autism Spectrum Disorder

Karin Prillinger, Stefan T. Radev, Kamer Doganay, Luise Poustka, Lilian Konicar

Frontiers in Human Neuroscience2022-04-257 citations

10.3389/fnhum.2022.838080

Interventions

Group 1: Intervention1: 24 sessions Slow-Cortical-Potential Neurofeedback-Training during an app. 3-month intervention period (20 participants with ASD) Group 2: Intervention 2: Treatment as usual and

Eligibility

Sex/Gender

All

Age

12 Years to 17 Years

Inclusion criteria

Inclusion criteria: - Adolescents with autism spectrum disorder - Age from 12.00 to 17.11 years, male and female - IQ> 70, right-handed - Informed Consent, ability to understand study information and instructions (sufficient knowledge of German), signed declarations of consent/assent of study participant and of parent/legal guardian

Exclusion criteria

Exclusion criteria: - Severe neurological or medical diseases or severe head injuries - Axis I diagnosis: Psychotic Disorder, Tic-, Tourette- or OC- Disorder, severe depression with suicidality - Simultaneous participation in pharmacological study, former neurofeedback training - Any implant or stainless steel graft or any other contraindications for MRI - Failure to comply with the study protocol or to follow the instructions of the investigating team

Design outcomes

Primary

Measure	Time frame
The primary endpoint of this study is the SCP (Slow-Cortical-Potential)-activity (SCP-differentiation in feedback and transfer condition, e.g. average µV-amplitude difference between required positivity and negativity) in the beginning of the training compared to the SCP-activity in the end of the training.	—

Secondary

Measure	Time frame
Secondary endpoints are the raw values ??of the questionnaires as well as the reaction times from psychological, computerised test from t0 (before the interventions) compared to t1 (after the interventions). Here, the target variables are autistic symptoms, comorbid characteristics, emotional processes, cognitive abilities and behavioral responses.	—

Countries

Austria

Contacts

Public ContactLilian Konicar

Medizinische Universität WienUniversitätsklinik für Kinder- & Jugendpsychiatrie

lilian.konicar@meduniwien.ac.at0043 1 40 400 37460

Outcome results

None listed