Efficacy of medical compression stockings with different interface pressures in patients with chronic venous insufficiency (CVI) of different severity

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

DRKS

Registry ID

DRKS00012259

Enrollment

Registered

2017-04-25

Start date

2017-04-26

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I87.20

Interventions

Group 1: Compression therapie with medical compression stockings with different interface pressure (Ccl 1, Ccl 2 and Ccl 3) in randomized order for 7 days each, no wash-out phase between the wearing p

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: chronic venous insufficiency CEAP C1-5; Willingness and ability of the subject to wear compression stockings as well as the doctor's instructions and to comply with the planned visits; Presence of written consent to participate in the study after a thorough investigation into the nature, significance, risks and scope of the clinical trial, as well as expected expected and undesirable effects of the trials; Sufficient German language skills both written and spoken

Exclusion criteria

Exclusion criteria: chronic venous ulcer (CEAP C6); Acute deep venous thrombosis; Peripheral Arterial Disease; Diabetes mellitus with neuropathy or peripheral arterial disorder; Absence of CVI; Non-existent mobility; Non-signed declaration of consent; Participation in another study; Pregnancy

Design outcomes

Primary

Measure	Time frame
volume of the lower limb (reduction of venous edema due to the applied compression therapy); measured in each case at the end of the 7-day wearing phase using BT600 (company Bauerfeind)	—

Secondary

Measure	Time frame
Clinical findings (influence of the application of different compression classes on the clinical symptoms of the CVI) assessed at the end of a 7-day wearing phase Venous ejection fraction (influence of the application of different compression classes on venous hemodynamic parameters in patients with CVI), measured by strain gauge plethysmography at the end of the 7-day wearing phase Interface pressure of the compression stockings measured with PicoPress after 7 days wearing phase Subjective assessment of patients during the wearing phases, measured daily by means of questionnaires on the quality of life	—

Measure

Time frame

Clinical findings (influence of the application of different compression classes on the clinical symptoms of the CVI) assessed at the end of a 7-day wearing phase Venous ejection fraction (influence of the application of different compression classes on venous hemodynamic parameters in patients with CVI), measured by strain gauge plethysmography at the end of the 7-day wearing phase Interface pressure of the compression stockings measured with PicoPress after 7 days wearing phase Subjective assessment of patients during the wearing phases, measured daily by means of questionnaires on the quality of life

—

Countries

Germany

Contacts

Public ContactManuela Reinhardt

Klinik und Poliklinik für Hautkrankheiten der Universitätsmedizin Greifswald

dermatologie@uni-greifswald.de03834866770

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026