Liver function, quantified by LiMAx test, after major abdominal and thoracic surgery. Comparison between open and laparoscopic approach.

Liver function, quantified by LiMAx test, after major abdominal and thoracic surgery. Comparison between open and laparoscopic approach. - LiSon Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00012247

Enrollment

Registered

2021-01-11

Start date

2014-03-25

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal resection, gastric resection

Interventions

Group 1: Surveillance of live function by LiMaX test in patients with open and laparoscopic throraco-abdominal surgery. Comparison with the ICG test and static live Parameter. Korrelation with live pe

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: transhiatal extended gastrectomy or esophagectomy.

Exclusion criteria

Exclusion criteria: pre-existing liver diseases (e. g. cirrhosis Child-Pough II-III), severe complications within the first ten days after surgery (Dindo IV°), allergy against substances used in the test, missing informed consent

Design outcomes

Primary

Measure	Time frame
Liver function measured by LiMAx test, preoperative between day 1-3 before scheduled operation and postoperative days 1, 3, 5 and 10.	—

Secondary

Measure	Time frame
Comparison with Indocyaningreen-test (Indocyaningreen-plasma-dilution-rate) 1-3 days preoerative and postoperative at day 1, 3, 5 and 10 and Duplex sonography (peak velocity of the Arteria hepatica and flow volume of the Vena Portae) 1-3 days preoperatve and postoperative on day 1, 3, 5 and 10.	—

Countries

Germany

Contacts

Public ContactMagnus Kaffarnik

Charite - Universitätsmedizin Berlin, Campus Virchow Klinik für Allgemein, Viszeral- und Transplantationschirurgie

magnus.kaffarnik@charite.de+40(0)30450652235

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026