Studying the efficacy of low intensity transcranial electrical stimulation in the acute treatment of migraine

Studying the efficacy of low intensity transcranial electrical stimulation in the acute treatment of migraine - Migraine

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011878

Enrollment

Registered

2017-04-21

Start date

2012-04-20

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G43

Interventions

Group 1: Low intensity transcranial alternating current stimulation (tACS, 0.4 mA, 140 Hz

duration: 10 minutes) Group 2: Placebo Stimulation

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Female and male patients (18-50 years) with migraine with or without aura and disease duration = 6 months (Headache Classification Committee of the International Headache Society, 2004).

Exclusion criteria

Exclusion criteria: significant chronic health disorders, diagnosed neuropsychiatric disorders, pregnancy or breast feeding, history of substance abuse or dependence, a history of neurological disorders other than migraine, an implanted pacemaker and cranial metallic hardware. age 50 years.

Design outcomes

Primary

Measure	Time frame
The primary endpoint of this study was the termination of the migraine attacks within two hours post stimulation.Patients were advised to document the degree of pain on a numerical analogue scale (NAS) with severity ratings ranging from 0 to 10 at onset of a migraine attack as well as 1 hour and 2, 4, 8, 24, and 48 hours thereafter	—

Secondary

Measure	Time frame
no secondary endpoint	—

Countries

Germany

Contacts

Public ContactAndrea Antal

UMG Klinische Neurophysiologie

aantal@gwdg.de0551398461

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026