M17.1 M18.1 M19.04
Conditions
Interventions
Group 1: Radiotherapy of the joint, 6 single fractions of 0.5Gy each twice a week up to a total dose of 3.0Gy, total treatment time three weeks
Group 2: Radiotherapy of the joint, 6 single fractions o
Sponsors
Klinik für Strahlentherapie und Radioonkologie, Universitätsklinikum des Saarlandes
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: - clinical diagnosis of a painful arthrosis of the knee joint or of joints of the hand with a minimum duration of symptoms of >= three months. - radiological proof of the arthrosis -typical clinical symptoms (pain after pressure, limitation of motion, swelling) - typical functional deficitis (limitation of mobility or of painless walking distance, limitation of grabbing function - sufficient general health status - age >= 40 years - written informed consent given
Exclusion criteria
Exclusion criteria: - previous radiotherapy to the joint involved - other cause of pain (trauma, rheumatoid arthritis - patients with arthrosis caused by a former rheumatoid arthritis can be included) - intense venous insufficiency - arterial occlusion disease - lymphedema - pregnancy, breastfeeding - intense psychical disorder - legal care for the patient by other persons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: pain relief tested three and twelve months after radiotherapy using the VAS scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of function (three and twelve months after radiotherapy, KOOS-SF or SF_SACRAH-scores, respectively) Improvement of general quality of life (three and twelve months after radiotherapy, SF-12 scores) Use of analgesic medication (complete duration of the trial, medication protocol) | — |
Countries
Germany
Contacts
Public ContactMarcus Niewald
Klinik für Strahlentherapie und Radioonkologie, Universitätsklinikum des Saarlandes
Outcome results
None listed