E10 E11 E12 E13 E14 Z04.2 V99 W49 W64 W87 W91 W92 W93 W94 X19 X29 X49 X59
Conditions
Interventions
Group 1: Standardised clinical investigation (angiopathy, neuropathy, nephropathy, retinopathy) as well as self-reported QoL in patients with diabetes mellitus
Group 2: Standardised clinical investiga
Sponsors
Abteilung für Endokrinologie und DiabetologieMedizinische Klinik I, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH, UK RUB
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Retrospective (protocol A) and prospective (protocol B) investigation: Admission for inpatient treatment or takeover after secondary relocation for surgical intervention due to an occupational accident insured by the German Statutory Accident Insurance system. Age between 18 and 65 years.
Exclusion criteria
Exclusion criteria: Retrospective Evaluation (Protocol A): Missing data on glucose homeostasis Prospective Study (Protocol B): •Missing informed consent •Insufficient proficiency in the German language or other communication problems •Severe cognitive impairment or psychiatric illness •Current malignant illness •Pregnancy •Other neurological disorders including cerebral ischemia, dementia, paraplegia, multiple sclerosis, Parkinson’s syndrome, spinal stenosis, and epilepsy with anticonvulsive treatment) Exclusion criteria for certain investigations of protocol B: Contraindications for certain methods including quantitative sensory testing (QST) or confocal corneal microscopy (in these cases the respective investigation is omitted). QST: •Skin diseases in the area of measurement •Local treatment in the area of measurement with topically applied local anaesthetics (= 7 days within the previous six weeks or > 7 days within the previous four months) or with capsaicin (during the previous six months). •Marked hypersensitivity of allodynia CCM: •Corneal transplantation (ceroplastic) •Eye surgery with conjunctival or corneal affection (e. g. in cases of cataract) during the previous three months •Nystagmus •Expected poor cooperation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of relative prevalence of diabetes among patients with occupational accidents requiring surgery and inpatient treatment compared to an age-, sex- and BMI-matched normal population | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessing, how concomitant diabetes modifies the course of inpatient treatment of occupational accidents: Are the length of stay in hospital (LOSIH), the rate of complications (e.g. sepsis, osteonecrosis, wound infections, necessary repeated surgery) and number, duration and success of successive rehabilitation cures provided by the statutory health insurance system different among diabetics and non-diabetics? Identify predictors of adverse results in diabetics: If diabetes mellitus is associated with increased risk, which single factors best predict the result? Is it the adjustment of metabolic control or are they possible complications of diabetes including diabetic neuropathy, angiopathy, retinopathy and nephropathy, which are associated with impaired prognosis (as single factors or in combination)? Does the quality of metabolic control correlate to prognosis? | — |
Countries
Germany
Contacts
Public ContactJohannes W. Dietrich
Sektion Diabetologie, Endokrinologie und Stoffwechsel, Universitätsklinik St. Josef-Hospital, UK RUB
Outcome results
None listed