Increase of the usage and effectiveness of colorectal cancer screening by means of targeted invitations with and without providing fecal immunochemical tests

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011858

Enrollment

20000

Registered

2017-03-20

Start date

2017-09-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Willingness to perform a stool blood test for colorectal cancer screening after sending out different invitation letters Willingness to perform a colonoscopy after a positive stool test result C18 C19 C20 K63.5 D12.2 D12.3 D12.4 D12.5 D12.6 D12.7 D12.8

Interventions

Group 1: Group A = Insured persons in group A receive a personal invitation letter from the AOK-BW, which describes early detection measures of colorectal cancer, invites them to carry out a quantitat

Eligibility

Sex/Gender

All

Age

50 Years to 54 Years

Inclusion criteria

Inclusion criteria: • Insured persons of the AOK-BW participating in the HZV-treaty (§ 73b SGB V) since 01.April 2017 or earlier

Exclusion criteria

Exclusion criteria: 1.) Letter from the AOK-BW to participants: • Deceased insured persons • Insured persons who have a nursing level • Insured persons with any kind of cancer diagnoses during insurance benefit (ICD = C*, D0*, D37*, D38*, D39*, D40*, D41*, D42*, D43*, D44*, D45*, D46*, D47*, D48*, D53*, D54*, D55*, D56*, D57*, D58*, D59*, D6*, D7*, D8*, D90*, Guaranty= Secured/condition after) • Insured persons where a curative colonoscopy has already been performed • Insured persons who where already addressed in another model project by the AOK-BW (see DRKS00006268) 2.) Analyses at the DKFZ: • Incorrect or implausible data to essential features in the data set

Design outcomes

Primary

Measure	Time frame
The primary endpoint is the usage rate of the test offer after receiving an invitation letter, as well as the usage rate of the test offer after recieving an invitation letter with subsequent reminder in comparison to the one-time letter, respectively within one year after the initial letter.	—

Secondary

Measure	Time frame
• The rate of positive test results • The rate of performing a colonoscopy after positive test • The rate of performing a colonoscopy after a negative test • The rate of newly discovered advanced colorectal neoplasia (carcinomas, advanced adenomas) • The positive predictive value of the test • The rate of performing a screening colonoscopy in general (even without taking the test offer) within one year	—

Measure

Time frame

• The rate of positive test results • The rate of performing a colonoscopy after positive test • The rate of performing a colonoscopy after a negative test • The rate of newly discovered advanced colorectal neoplasia (carcinomas, advanced adenomas) • The positive predictive value of the test • The rate of performing a screening colonoscopy in general (even without taking the test offer) within one year

—

Countries

Germany

Contacts

Public ContactLaura Gruner

Deutsches Krebsforschungszentrum (DKFZ) Abteilung Klinische Epidemiologie und Alternsforschung (C070)

l.gruner@dkfz.de06221421347

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 27, 2026