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3D-MULTimodal Atrial SubstrAte MAPping in Atrial Fibrilliation – Feasibility and potential clinical relevance - The MULTASA-MAP Study

3D-MULTimodal Atrial SubstrAte MAPping in Atrial Fibrilliation – Feasibility and potential clinical relevance - The MULTASA-MAP Study - MULTASA-Map Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00011810
Enrollment
30
Registered
2017-03-10
Start date
2017-02-23
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I48.1

Interventions

Group 1: Following maps were created in all patients in the right and left atrium. 1. Voltage Map (sinusrhythm) 2. LAT Map (sinusrhythm) 3. CFAE Map (atrial fibrillation) 4. Global Map (atrial fibrill

Sponsors

Klinikum der Universität München, Campus Großhadern
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ?Documented persistent atrial fibrillation (duration > 4 weeks, < 12 months) ?Planned catheter ablation for symptomatic AF ?First left atrial ablation procedure ?Sinus rhythm prior to the procedure ?Age 18-75 years

Exclusion criteria

Exclusion criteria: ?Contra-indications to catheter ablation therapy ?Patients with paroxysmal ( 55 mm ?LA thrombus ?Previous LA substrate modification/surgery ?Severe structural heart disease, ?Hypertrophic cardiomyopathy ?Mitral prosthesis ?Unstable angina ?Uncontrolled hyperthyroidism ?Stroke or TIA within 6 months ?Myocardial infarction within 2 months ?Cardiac surgery within 3 months ?Thrombocytosis, thrombocytopenia ?Any condition contraindicating chronic anticoagulation ?Pregnancy ?Life expectancy <1year

Design outcomes

Primary

MeasureTime frame
1. Feasibility of 3D-multimodal reconstruction representing an atrial map with respect to following parameters: voltage, excitation/conduction, CFAEs, spiral activation patterns in each patient. 2. Junction of the different maps.

Secondary

MeasureTime frame
1. Coincidence of the different phenomena and outcome of the procedure. 2. Quantitative AF burden (in % of FU time, 12 weeks of blanking period post ablation). 3. Safety

Countries

Germany

Contacts

Public ContactArmin Luik

Städtisches Klinikum Karlsruhe Medizinische Klinik IV

luik@klinikum-karlsruhe.de0721-9742901

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026