Linking Substrate Based Electrogram Characteristics with Activation Patterns to Develop Individualized Ablation Strategies for Atrial Fibrillation

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011808

Enrollment

Registered

2020-04-01

Start date

2019-10-25

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I48.0 I48.1

Interventions

Group 1: Single arm study. All patients are examined equally. Creation of Voltage, CFAE and Rotors Map. Compilation of the maps and analysis of a local overlap between the different mapping phenomena:

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Clinical indication for catheter ablation due to atrial fibrillation or atrial flutter.

Exclusion criteria

Exclusion criteria: - Left atrium > 55mm - Left atrial thrombus - Instable Angina pectoris / present myokardial infarction < 3 month - Mitral regurgiation - NYHA III-IV - Stroke/TIA < 3 month - uncontrolled hyperthyreodism - Pregnancy - Life expectancy < 1 year - Contraindication for oral anticoagulation - Mitral prothesis

Design outcomes

Primary

Measure	Time frame
Compilation of the maps and analysis of a local overlap between the different mapping techniques: CFAEs, rotors, low-voltage	—

Secondary

Measure	Time frame
Determination of the excitation patterns in the retrospective analysis of the data. Division into substrate-based, functional, active and passive.	—

Countries

Germany

Contacts

Public ContactArmin Luik

Städtisches Klinikum Karlsruhe Medizinische Klinik IV

luik@klinikum-karlsruhe.de0721-9742901

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026