D-dimer plasma levels and risk for thromboembolism after surgery for intracranial tumors with intraoperative administration of intermittent pneumatic compression of the legs

D-dimer plasma levels and risk for thromboembolism after surgery for intracranial tumors with intraoperative administration of intermittent pneumatic compression of the legs - IPK-IOP

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011783

Enrollment

108

Registered

2017-02-20

Start date

2013-03-14

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I80.28

Interventions

Group 1: Pre- and postoperatively, Doppler-sonography of the lower extremity is performed for diagnosis/exclusion of deep venuous thrombosis. From the first postoperative day on, thromboprophylaxis is

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Elective surgery for intracranial pathology via craniotomy.

Exclusion criteria

Exclusion criteria: Minors or pregnant patients, Administration of blood-products in the perioperative period, abnormal coagulation status, preoperative infection, revision surgery after initial surgery, liver disease, preoperative deep venuous thrombosis or thrombophlebitis. Decompensated cardiac insufficiency, Erysipel, severe arterial hypertonus, soft tissue damage of the lower extremity, neuropathy and occlusion of lymph vessels.

Design outcomes

Primary

Measure	Time frame
Incidence of deep venuous thrombosis in patients undergoing surgery for intracranial pathology with/without IPC, determined by Doppler sonography of the legs within the first week after surgery.	—

Secondary

Measure	Time frame
1. D-dimer plasma levels on the 3rd postoperative day in patients with/without IPC; threshold for screening? 2. Quantification of risk reduction for deep venuous thrombosis by IPC with respect to duration of surgery and other clinical variables	—

Countries

Germany

Contacts

Public ContactJulian Prell

Klinik und Poliklinik für Neurochirurgie der Martin-Luther-Universität Halle-Wittenberg

julian.prell@uk-halle.de03455571909

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 24, 2026