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Evaluation of the effect of vital tooth bleaching on its biological and physical properties

Evaluation of the effect of vital tooth bleaching on its biological and physical properties

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00011779
Enrollment
85
Registered
2017-02-17
Start date
2017-02-17
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulp damage through Vital Tooth bleaching

Interventions

Group 1: "In-office bleaching": Philips Zoom in-office whitening gel 25 % H2O2, single application 3 x 15 minutes Treated premolar will be extracted on the following day. Group 2: "In-office bleachin

Sponsors

University of ZurichCenter for Dental Medicine (ZZM)Clinic of Preventive Dentistry, Periodontology, and Cariology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 35 Years

Inclusion criteria

Inclusion criteria: Patients aged 16-35, in active orthodontic treatment with vital premolars without pathological finding, which are to be extracted in the course of their orthodontic treatment, prior to application of any orthodontic force

Exclusion criteria

Exclusion criteria: Non-vital / root canal-treated premolars, premolars with open carious lesions or deep fillings, pregnancy

Design outcomes

Primary

MeasureTime frame
Histologic assessment will be performed by one blinded calibrated examiner. Using a light microscope, histopathological events will be evaluated and classified by a descriptive analysis.

Secondary

MeasureTime frame
One day after treatment, the treated premolar will be assessed for following points: Assessment of the bleaching effect, i.e. color change (measured by VITA Easyshade® Advance, Vita Zahnfabrik AG, Germany) Assessment of changes in tooth vitality through cooling spray (positive/negative) Assessment of change of tooth surface temperature through treatment Assessment of tooth sensitivity (VAS) - 1. perceived self-reported sensitivity 2. reaction to gentle air blow

Countries

Croatia, Switzerland

Contacts

Public ContactValerie Steiger-Ronay

University of ZurichCenter for Dental Medicine (ZZM)Clinic of Preventive Dentistry, Periodontology and Cariology

valerie.steiger@zzm.uzh.ch+41 44 634 39 36

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026