G20
Conditions
Interventions
Group 1: The study has a cross-over design. The patients are randomized into two groups (A and B) including max.10 patients. Group A receives the cognitive stimulation during the first phase (0 - 8 we
Sponsors
Universitätsklinik Köln, Medizinische Psychologie |Neuropsychologie und Gender Studies
Eligibility
Sex/Gender
All
Age
50 Years to 100 Years
Inclusion criteria
Inclusion criteria: Clinical diagnosis conducted by neurologist or psychiatrist, mild to moderate dementia; Age: 50 years or older, mother tongue Dutch or very good skills in Dutch language; Good or sufficiently corrected vision and hearing
Exclusion criteria
Exclusion criteria: MMSE overall score below 10 points; Major depression (operationalized by the CDS >12) (Rasmus, 2009); Alcohol and drug abuse in the last three years; Acute suicidal tendencies, acute psychotic symptoms, other serious / life-threatening comorbidities that oppose study participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognition: times of measurement: Baseline, Posttest, Follow up (after 6 weeks) CERAD (+ Trail Making A+B, letter fluency), Clock Drawing Test | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient-Related Endpoints: Quality of life: measuring instruments: EQ-5D-5L (self-administered), EQ-5D-5L (proxy-administered) Quality of Life in Dementia (Qualidem, proxy-administered) Depression; Measuring instruments: geriatric depression scale (GDS, self-administered), Cornell depression scale (CDS, proxy-administered); Behavioral and psychiatric symptoms; Measuring instrument: neuropsychiatric inventory (NPI, proxy-administered); Activities of daily life (ADLs); Measuring instrument: Barthel Index (proxy-administered); All endpoints are collected at the time of pre- and post-testing (short-term effect) and after 6 weeks (long-term effect) | — |
Countries
Netherlands
Contacts
Public ContactMiriam Dorn
Medizinische Psychologie | Neuropsychologie und Gender Studies
Outcome results
None listed