Effects of a-Cyclodextrin (ACD) on postprandial glucose homeostasis and incretin levels in healthy human volunteers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011759

Enrollment

Registered

2017-03-17

Start date

2017-03-20

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy volunteers

Interventions

Group 1: oral glucose tolerance test (75g glucose and 10g inulin solved in 300ml water) blood samples will be taken at timepoints 0,15,30,60,90,120,180, and 240 minutes hydrogencontent in breath will

Eligibility

Sex/Gender

All

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: healthy volunteers between 18 and 30 years of age, BMI <30 kg/km2, non-smoker, written informed consent

Exclusion criteria

Exclusion criteria: smokers, disorders affecting nutrient absorption, digestion, metabolism, and excretion, chronic disorders e.g. hepatitis B and C, diabetes mellitus, acute infections, other disorders in the past 3 months, intolerance to acetaminophen, contraceptive, pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
bloodglucose will be measured using Hemocue at timepoints 0,15,30,60,90,120,180, and 240 minutes	—

Secondary

Measure	Time frame
PYY, GLP-1, and GIP will be analysed using ELISA at timepoints 0,15,30,60,90,120,180, and 240 minutes	—

Countries

Germany

Contacts

Public ContactThomas Skurk

Technischen Universität MünchenZIEL Institute for Food and HealthCore Facility für Humanstudien

skurk@tum.de08161-712007

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026