Impact of the use of ultrasound contrast agent on the detection of thrombi in the left atrial appendage during transesophageal echocardiography (CONDOR)

Impact of the use of ultrasound contrast agent on the detection of thrombi in the left atrial appendage during transesophageal echocardiography (CONDOR) - CONDOR

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011716

Enrollment

100

Registered

2017-02-23

Start date

2017-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I48

Interventions

Group 1: In patients with atrial fibrillation and the clinical indication for a TOE the TOE will first be performed without the use of echo contrast agent and the existence of thrombi in the LAA will

afterwards (during the same TOE examination) an echo contrast agent will be administered and the evaluation will be repeated ("Thrombi yes / no / uncertain")

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: age > 18 years; documented atrial fibrillation (paroxysmal or persistent or permanent); clinical indication for TOE because of scheduled cardioversion or LAA closure; signed informed consent

Exclusion criteria

Exclusion criteria: history of LAA closure (either interventional or surgical); allergy against SonoVue; intracardiac shunt, severe pulmonary hypertension, uncontrolled arterial hypertension, acute respiratory distress syndrome

Design outcomes

Primary

Measure	Time frame
frequency of detected thrombi in the LAA by transesophageal echocardiography in dependance of the use of echo contrast agent (with contrast agent /wo contrast agent)	—

Secondary

Measure	Time frame
size of the LAA ostium (minimal/ mean/ maximal diameter) with and without contrast agent	—

Countries

Germany

Contacts

Public ContactHenning Ebelt

Katholisches Krankenhaus Erfurt

hebelt@kkh-erfurt.de+49-361-6541111

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026